Treatment of Cancer

Pat Price . Karol Sikora

ISBN: 9781482214949

Autor: Price

Año Edición: 2015

Edición: 6 th

Páginas: 826

Formato: 21 x 27 cm.

Encuadernación: Tapa Dura

Peso: 5 Kg.

178,00 €

169,10 €

-5%

178,00 €

IVA Incluido
Envío Gratis

Treatment of Cancer, Sixth Edition is a multi-authored work based on a single theme—the optimal treatment of cancer. A comprehensive guide to modern cancer treatment, it supports an integrated approach to patient care including radiotherapy, chemotherapy and surgery.

The sixth edition has been completely updated to create a useful, practical guide focused on the management of individual tumour types. The characteristic didactic approach to patient care of previous editions is retained, but now with greater consideration to the options available. This book is a valuable resource for trainees, oncologists, radiation oncologists, surgical oncologists, and haematologists.

Features

  • Provides a comprehensive guide to modern cancer treatment focusing on patient management
  • Supports an integrated approach to patient care involving radiotherapy, chemotherapy, and surgery where appropriate
  • Features supporting online content including clinical practice guidelines, epidemiology and outcome statistics, patient support resources, and more.
  • Authored by high-profile opinion leaders, making it essential reading for trainees and physicians
  • Includes access to an eBook version with purchase of the printed book
Table of Contents
Central Nervous System
Pathology
Imaging
Treatment of Central Nervous System Tumours
Individual Tumours
References
Ocular and Adnexal Tumours
Paediatric Tumours
Other Paediatric Tumours
Adult Tumours
References
Head and Neck Cancer
Introduction
Organization of Services for Patients
Incidence
Head and Neck Cancer Is a Global Problem
Outcome
Aetiology
Problem of Second Primary Tumours
Strategies for Prevention
General Principles of Surgery
General Principles of Radiotherapy
General Principles of Combined Treatment in Head and Neck Carcinoma
Palliative Care
Staging and Prognosis
Assessment of Patients
Role of Prophylactic Treatment to the Neck In Patients with Clinical
Negative Neck and Primary Tumours of the Head and Neck
Management of Potentially Operable Cervical Lymphadenopathy
Treatment of Inoperable Nodal Disease After Previous Radiotherapy
Carcinoma of the Lip
Tumours of the Oral Cavity
Carcinoma of the Oropharynx
Hypopharynx
Posterior Pharyngeal Wall
Larynx
Nasopharynx
Tumours of the Nose and Paranasal Sinuses
Tumours of the Ear
Rare and Unusual Tumours of the Head and Neck
References
Thyroid
Introduction
Epidemiology
Aetiology
Pathogenesis
Pathology and Natural History
Diagnostic Evaluation
Tumour, Nodes, Metastases
Management of Differentiated Thyroid Cancer
Radioactive Iodine Ablation of Residual Thyroid Tissue
Follow-Up
Treatment of Metastatic Disease
Dosimetry of 131I Therapy
Complications of Radioiodine Treatment
External-Beam Radiotherapy and Systemic Therapies
Management of Anaplastic Carcinoma
Management of Medullary Thyroid Cancer
Management of Thyroid Lymphoma
Future Prospects
References
Endocrine and Neuroendocrine Tumours
Apud Concept and Apudomas
Pituitary Tumours
Medullary Thyroid Carcinoma
Gastro-Entero-Pancreatic Endocrine Tumours
Carcinoid Tumours
General Oncology Principles for Systemic Management of Net
Phaeochromocytoma
Multiple Endocrine Neoplasia
Parathyroid Adenoma and Carcinoma
Adrenocortical Tumours
References
Bibliography
Breast Cancer
Epidemiology 
Identification of High-Risk Groups
Breast Cancer Chemoprevention
Presentation and Investigation
Staging
Screening
Molecular Genetics
Pathology
Surgery for Early Breast Cancer
Adjuvant Treatment
Locally Advanced Disease
Loco-Regional Recurrence
Secondary Breast Cancer
Complications of Metastatic Breast Cancer
Acknowledgements
References
Lung Cancer
Epidemiology and Aetiology
Classification
Prevention and Screening
Diagnosis and Staging
Management of Non-Small-Cell Lung Cancer
Management of Small-Cell Lung Cancer
Palliative Care
References
Oesophageal Cancer
Introduction
Epidemiology and Aetiological Factors
Clinical Manifestations
Management of Localized (Operable) Oesophageal Cancer
Management of Locally Advanced Oesophageal Cancer
Management of Advanced Oesophageal Cancer
References
Bibliography
Hepatocellular Carcinoma 
Introduction 
Incidence 
Hepatocellular Carcinoma 
References
Pancreas 
Incidence and Mortality 
Aetiology 
Genetics 
Anatomy 
Pathology and Staging 
Symptoms and Signs 
Natural History 
Investigation
Treatment
Special Considerations in the Management of Pancreatic Cancer
References
Biliary Tract
Tumours of the Bile Duct (Cholangiocarcinoma)
Gall Bladder Cancer
Future Trends
References
Gastric Cancer
Incidence
Aetiology
Diagnosis
Pathology
Molecular Pathogenesis
Staging
Treatment
Future Directions
References
Bladder Cancer
Introduction
Epidemiology
Aetiology
Genetics of Bladder Cancer
Pathology
Clinical Presentation and Investigation
Management
Management of Low-Grade Superficial Non-Muscle-Invasive Bladder Cancer 
High-Grade Non-Muscle-Invasive Bladder Cancer 
Radiotherapy and Systemic Treatments for Superficial Disease
Management of Invasive Bladder Cancer
Adjuvant Chemotherapy
Surgical Treatment
Radiotherapy in the Management of Muscle-Invasive Bladder Cancer
Management of Advanced Disease
Bibliography 
References
Prostate Cancer
Introduction
Epidemiology and Aetiology
Prevention and Screening
Pathogenesis
Pathology and Staging
Clinical Features
Diagnosis and Staging
Principles of Management
Management of Organ-Confined Disease
Management of Locally Advanced Disease
Management of Recurrent Disease After Radical Local Therapy
Management of Metastatic Disease
Concluding Remarks
References
Colorectal Cancer
Introduction
Incidence and Cause
Diagnosis and the Multidisciplinary Team
Pathology of Colorectal Tumours
Molecular Pathogenesis of Colorectal Carcinoma
Pathology of Invasive Colorectal Cancers
Treatment
Follow-Up After Initial Treatment
Summary and Future Developments
National Health Service Guidelines
Conclusions
References
Bibliography
Anus
Anatomy
Pathology
Epidemiology and Risk Factors
Presentation
Diagnostic Work-Up and Staging
Management
Lymph-Node Metastases
Prognostic Factors and Outcome
Extra-Pelvic Metastases
Radiation Therapy Alone
Surgery
Non–Squamous Cell Cancers
Peri-Anal Cancer
Patients With Human Immunodeficiency Virus Infection
References
Germ-Cell Cancer of the Testis and Related Neoplasms
Introduction
Background 
Diagnosis and Staging
Assessment and Staging of Disease
Serum Markers
Stage 1 Disease and Risk of Relapse
Treatment
Metastatic Disease
Complications of Treatment
References
Renal Cell Cancer
Introduction and Epidemiology
Classification of Renal Tumours
Inherited Syndromes and the Molecular Biology of Renal Cell Carcinoma
Risk Factors
Clinical Features
Clinical Evaluation and Staging
Localized Disease
Disease Relapse
Metastatic Disease – Surgical Management
Metastatic Disease – Prognostic Factors
Metastatic Disease – Non Surgical Management
Treatment Options in Non-Clear Cell Histology
Sequencing of Treatments: First-Line, Second-Line and Beyond
Conclusion
References
Ovary and Fallopian Tubes
Epithelial Tumours of the Ovary
Low Malignant Potential Tumours of the Ovary
Non-Epithelial Tumours of the Ovary
References
Endometrial Cancer 
Pathogenesis 
Histopathology 
Pathologic Features Affecting Prognosis 
Investigation 
Staging and Tumour Classification 
Treatment 
Follow-Up 
References 
Bibliography
Cervix 
Incidence and Causes 
Pathology 
Prevention and Treatment of Pre-Invasive Disease 
Cervical Screening 
Clinical Features of Invasive Carcinoma of the Cervix 
Investigations for Invasive Disease 
Staging and Prognostic Factors 
Treatment 
Complications of Treatment 
New Developments 
Conclusions 
Acknowledgements 
References
Carcinoma of the Vagina and Vulva 
Carcinoma of Vagina 
Carcinoma of the Vulva
References
Gestational Trophoblastic Neoplasia 
Introduction
Genetics and Pathology
Epidemiology and Aetiological Factors 
Human Chorionic Gonadotrophin 
Clinical Features 
Management and Investigations 
Summary 
References 
Bibliography
Non-Melanoma Skin Cancer 
Introduction 
Aetiology 
Familial Skin Cancer Syndromes 
Xeroderma Pigmentosum 
Pre-Malignant Conditions 
Actinic Keratosis and Bowen’s Disease 
Basal Cell Carcinoma 
Squamous Cell Carcinoma 
Primary Cutaneous Lymphoma 
Primary Cutaneous T-Cell Lymphoma 
Primary Cutaneous B-Cell Lymphoma 
Other Non-Melanoma Skin Cancers 
Merkel Cell Carcinoma 
Langerhans Cell Histiocytosis 
References
Malignant Melanoma 
Introduction 
Epidemiology 
Aetiology 
Prevention 
Tumour Biology 
Diagnosis 
Pathology 
Staging and Prognosis 
Treatment of Primary Melanoma 
Loco-Regional Recurrent Disease
Distant Metastatic Disease 
Targeted Therapies 
NRAS Mutated Melanoma 
Kit Mutated Melanoma 
Targeted Agents in Uveal Melanoma 
Systemic Therapies 
Conclusions 
References
Primary Bone Tumours 
Introduction 
Incidence and Aetiology 
General Principles of Management 
Osteosarcoma 
Ewing Sarcoma 
Chondrosarcoma 
Other Primary Bone Tumours 
Key References 
References
Soft Tissue Sarcomas 
Introduction 
Aetiology 
Clinical Evaluation 
Pathology 
Staging 
Management of the Extremity, Trunk, or Head and Neck Primary Tumour
Adjuvant Chemotherapy
Functional Outcome
Treatment of Local Recurrence
Radiotherapy Alone
Treatment of Unresectable or Locally Advanced Soft Tissue Sarcoma 
Management of the Retroperitoneal Primary Lesion 
Treatment of Metastatic Soft Tissue Sarcoma 
Management of Gastrointestinal Stromal Tumours 
Desmoid Tumours 
References
Leukaemias 
Introduction 
Acute Leukaemias 
Chronic Leukaemias 
Acknowledgements 
References
Hodgkin Lymphoma 
Introduction 
Diagnosis, Staging and Choice of Treatment 
First-Line Treatment 
Treatment of Relapsed Hodgkin Lymphoma 
Special Considerations 
New Drugs 
Acknowledgements 
Key References 
References
Non-Hodgkin Lymphoma 
Epidemiology and Risk Factors, Classification, Staging and Molecular Pathogenesis of Non-Hodgkin Lymphoma 
Aggressive Non-Hodgkin Lymphoma 
Primary Mediastinal (Thymic) Large B-Cell Lymphoma 
Central Nervous System Lymphoma and Prophylactic Central Nervous System Chemotherapy 
Burkitt Lymphoma 
Mantle Cell Lymphoma 
Human Immunodeficiency Virus - Associated Lymphoma 
Peripheral T-Cell Lymphoma 
Indolent Non-Hodgkin Lymphoma 
Marginal Zone Lymphoma 
Future Developments 
Key Reference 
References
Multiple Myeloma 
Introduction 
Incidence and Aetiology 
Pathogenesis and Biology 
Clinical Features and Complications 
Investigation, Diagnosis and Staging 
Prognostic Factors and Staging 
Course of the Disease 
When to Start Treatment and Criteria For Response 
General Aspects of Care 
Myeloma Therapy 
Radiotherapy 
High-Dose Therapy and Stem-Cell Transplantation 
Maintenance and Consolidation Therapy 
Bisphosphonates 
Refractory and Relapsed Disease 
New Approaches to Treatment 
Other Related Conditions 
References
Paediatric Oncology 
General Introduction 
Epidemiology of Childhood Cancer 
Childhood Leukaemia 
Hodgkin’s Lymphoma 
Nodular Lymphocyte Predominant Hodgkin Lymphoma 
Non-Hodgkin Lymphoma 
Burkitt’s Lymphoma and Diffuse Large B-Cell Lymphoma 
Precursor T- and B-Cell Lymphoblastic Lymphoma 
Anaplastic Large Cell Lymphoma 
Liver Cancers 
Neuroblastoma 
Ewing’s Family Tumours 
Treatment 
Osteosarcoma 
Renal Tumours 
Staging Investigations 
Malignant Germ Cell Tumours 
Non–Central Nervous System Tumours 
Rhabdomyosarcoma 
Central Nervous System Tumours 
Primitive Neuroectodermal Tumours 
Astrocytic Tumours 
Central Nervous System Germ Cell Tumours 
Primitive Neuroectodermal Tumours 
Astrocytic Tumours 
Central Nervous System Germ Cell Tumours 
Atypical Teratoid Rhabdoid Tumours 
Central Nervous System Tumours In Infants and Very Young Children 
Organ Toxicity 
Psychological Aspects of Childhood Cancer 
Management of Acute Neurological Complications 
References
AIDS–Related Malignancy 
Introduction 
Aids-Defining Malignancies 
Non-Aids – Defining Malignancies 
Other Non-Aids – Defining Malignancies 
Castleman’s Disease 
References
Clinical Cancer Genetics 
Introduction 
Cancer Pre-Disposition Genes 
Research Approaches For the Identification of Cancer Pre-Disposition Genes 
Cancer Risks Associated With Cancer Pre-Disposition Genes 
Management of A Known Or Suspected Cancer Pre-Disposition Gene Mutation Carrier 
Summary 
Key References 
References
Lifestyle Factors in Cancer Survivorship 
Adiposity and Weight Gain 
Diet and Dietary Supplements 
Foods Supplements 
Carcinogen Avoidance 
Smoking 
Alcohol 
Physical Activity After Cancer 
Evidence that Physical Activity Improves Survival and Reduces Relapse Rates 
Summary 
References
ISBN9781482214949
AutorPrice
Año Edición2015
Edición6 th
Páginas826
Formato21 x 27 cm.
EncuadernaciónTapa Dura
Peso5 Kg.