Neonatal and Pediatric Pharmacology

Yaffe . Aranda

Autor: Yaffe

ISBN: 9780781795388

Encuadernación: Tapa Dura

Año Edición: 2011

Edición: 4ª ed.

Páginas: 1042

Peso: 2.5 kg.

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Written by experts at the forefront of current research and clinical practice, Neonatal and Pediatric Pharmacology provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents. Coverage includes specific recommendations for all major drug classes and diseases, a detailed section on drugs and the newborn, and chapters on specific treatment settings such as the pediatric intensive care unit and emergency room. Also included are chapters on adverse effects and interactions and state-of-the-art discussions on pharmacokinetics, pharmacodynamics, pharmacogenetics, pharmacogenomics, pharmacoproteomics, drug development, and clinical trials in infants and children. Appendices include a neonatal formulary and a pediatric formulary.

The Fourth Edition includes updated information on drug interactions and regulatory issues. New chapters cover nutrient supplements and biotransformation of medications by the human placenta.


    NEW: New chapter on nutrient supplements
    NEW: New chapter on biotransformation of medications by human placenta
    NEW: Updated information on drug interactions
    NEW: Updated information on federal legislation
    Evidence-based discussion of drugs in pediatric population
    State-of-the-art discussion of what is known about the basic science of drugs in pediatrics
    Written and edited by the foremost authorities in pediatric clinical pharmacology

Table of Contents


    1: Introduction and Historical Perspectives
    2: Clinical Pharmacokinetics in Infants and Children
    3: Drug Action and Therapy in the Infant and Child
    4: Drug Metabolism and Disposition in Infants and Children
    5: Pharmacogenetics, Pharmacogenomics, and Pharmacoproteomics
    6: Compliance with Pediatric Medication Regimens
    7: Clinical Trials Involving Children: History, Rationale, Regulatory Framework, and Technical Considerations
    8: Ethics of Drug Research in Pediatric Populations
    9: Therapeutic Drug Monitoring
    10: Drug Formulations


    11: Developmental Toxicology
    12: Biotransformation of Medications by Human Placenta
    13: Maternal Drug Intake and the Newborn
    14: Principles of Neonatal Pharmacology
    15: Perinatal Origins of Adult Defects in Drug Metabolism
    16: Renal Function and Excretion of Drugs in the Newborn
    17: The Excretion of Drugs and Chemicals in Human Milk
    18: Drugs for Hyperbilirubinemia
    19: Drugs and Lung Development
    20: Pharmacologic Treatment of Neonatal Apnea
    21: Drugs and Perinatal Brain Injury
    22: Antiretroviral Pharmacology in Pregnant Women and Newborns


    23: Therapeutic Applications in Pediatric Intensive Care
    24: Drug Therapy in the Pediatric Emergency Department
    25: Drug Therapy in the Adolescent
    26: Topical Medications
    27: Ophthalmologic Drugs in Infants and Children


    28: Sulfonamides
    29: Penicillins, Cephalosporins, and Other Beta-Lactams
    30: Aminoglycosides and Glycopeptides
    31: Fluoroquinolones
    32: Macrolides, Chloramphenicol, and Tetracyclines
    33: Anthelminthic Drugs in Children
    34: Antituberculosis Drugs
    35: Antifungal Agents
    36: Antiviral Drugs: Treatment of the Fetus and Newborn
    37: Anticonvulsants
    38: Psychopharmacology in Children and Adolescents
    39: Antihistamine Drugs
    40: Antiasthmatics
    41: Antipyretics
    42: Cardiovascular Drugs
    43: Diuretics
    44: Clinical Pharmacology of Antineoplastic Drugs
    45: Immunosuppressive and Immunomodulatory Drugs
    46: Analgesic Agents
    47: Local Anesthetics for Infants and Children
    48: Nonsteroidal Anti-inflammatory Drugs
    49: Antihypertensive Agents
    50: Gastrointestinal Drugs
    51: Glucocorticoids
    52: Insulin and Diabetes Mellitus
    53: Thyroid Hormones
    54: Growth Hormone
    55: Hematologic Agents
    56: Nutrient Supplements
    57: Childhood Vaccines


    58: Epidemiology of Adverse Drug Effects
    59: Mechanisms of Adverse Drug Reactions
    60: Medication Errors
    61: Pediatric Poisonings and Antidotes
    62: Use of Herbal Products in Children: Risks and Unproven Benefits
    63: Neonatal Abstinence Syndromes
    64: Drug Interactions in Newborns and Children


    65: Drug Formulary for the Newborn
    66: Pediatric Drug Formulary

EncuadernaciónTapa Dura
Año Edición2011
Edición4ª ed.
Peso2.5 kg.