Biochemistry, Cell and Molecular Biology, and Genetics. An Integrated Textbook

Integrates biochemical, molecular, and cellular health and disease processes into one essential text!

Biochemistry, Cell and Molecular Biology, and Genetics: An Integrated Textbook by Zeynep Gromley and Adam Gromley is the first to cover molecular biology, cell biology, biochemistry (metabolism), and genetics in one comprehensive yet concise resource. Throughout the book, these topics are linked to other basic medical sciences, such as pharmacology, physiology, pathology, immunology, microbiology, and histology, for a truly integrated approach.

• Easy-to-read text enhances understanding of underlying molecular mechanisms of disease
• Nearly 1000 illustrations and tables help reinforce chapter learning objectives
• Textboxes throughout make connections with other preclinical disciplines
• End of unit higher order clinical vignette questions with succinct explanations help integrate basic science topics with clinical medicine

This textbook provides a robust review for medical students preparing for courses as well as exams. Dental, pharmacy, physician's assistant, nursing, and graduate students in pre-professional/bridge programs will also find this a beneficial learning tool.

This book includes complimentary access to a digital copy on https://medone.thieme.com.

CONTENTS:

UNIT I
Chapter 1. Anatomy of the Cell and Organelles
Chapter 2. DNA Replication, Gene Mutations, and Repair
Chapter 3. Transcription and Regulation of Transcription
Chapter 4. Translation and Regulation of Translation

UNIT II
Chapter 5. Cytoskeleton
Chapter 6. Protein Sorting, Modifications, and Intracellular Traffic
Chapter 7. Membrane Transport
Chapter 8. Extracellular Matrix
Chapter 9. Cell Adhesion and Membrane Junctions
Chapter 10. Signal Transduction
Chapter 11. Cell Cycle and Control of the Cell Cycle
Chapter 12. Stem Cells and Cellular Differentiation
Chapter 13. Cell Injury, Apoptosis, Necrosis
Chapter 14. Hallmarks of Cancer and Cancer Biology
Chapter 15. Molecular Principles of Cancer Treatments and Therapies

UNIT III
Chapter 16. Enzymes and Enzyme Kinetics
Chapter 17. Regulation of Enzyme Activity
Chapter 18. Structure and Function of Proteins
Chapter 19. Molecular, Cellular and Biochemical Techniques
Chapter 20. Plasma Proteins and Diagnostic Use of Enzymes

UNIT IV
Chapter 21. Digestion and Absorption of Carbohydrates
Chapter 22. Glycolysis
Chapter 23. Metabolism of Fructose, Galactose and the Pentose Phosphate Pathway
Chapter 24. Glycogen Metabolism
Chapter 25. Gluconeogenesis
Chapter 26. Pyruvate Dehydrogenase and Tricarboxylic Acid (TCA) Cycle
Chapter 27. Electron Transport Chain and Oxidative Phosphorylation
Chapter 28. Oxygen Toxicity and Antioxidants
Chapter 29. Oxidation of Fatty Acids and Ketogenesis
Chapter 30. Acid Base Chemistry and Acid Base Disorders
Chapter 31. Glucose Homeostasis and Maintenance of Blood Glucose Concentrations

UNIT V
Chapter 32. Digestion and Absorption of Proteins
Chapter 33. Nitrogen Metabolism
Chapter 34. Amino Acid Metabolism
Chapter 35. Amino Acid Derivatives
Chapter 36. Porphyrin/Heme Metabolism and Iron Homeostasis
Chapter 37. Nucleotide Metabolism
Chapter 38. Vitamins in One Carbon Metabolism

UNIT VI
Chapter 39. Digestion and Absorption of Lipids
Chapter 40. Synthesis of Fatty Acids and Triacylglycerol
Chapter 41. Metabolism of Membrane Lipids and Lipid Derivatives
Chapter 42. Cholesterol Metabolism
Chapter 43. Blood Lipoproteins
Chapter 44. Steroid Hormones and Vitamin D
Chapter 45. Nutrition and Metabolism
Chapter 46. Vitamins and Minerals

UNIT VII
Chapter 47. DNA Packaging and Meiosis
Chapter 48. Cytogenetics: Chromosomal Basis of Human Diseases
Chapter 49. Autosomal Dominant and Recessive Inheritance
Chapter 50. Sex-Linked and Non-Traditional Modes of Inheritance
Chapter 51. Population Genetics
Chapter 52. Genomic Imprinting and Epigenetics
Chapter 53. Gene Interactions and Multifactorial Inheritance
Chapter 54. Personalized Medicine
Chapter 55. Developmental Genetics
Chapter 56. Cancer Genetics