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Current, comprehensive, and evidence-based Braunwald’s Heart Disease remains the most trusted reference in the field and the leading source of reliable cardiology information for practitioners and trainees worldwide. The fully updated 12th Edition continues the tradition of excellence with dependable, state-of-the-art coverage of new drugs, new guidelines, more powerful imaging modalities, and recent developments in precision medicine that continue to change and advance the practice of cardiovascular medicine. Written and edited by global experts in the field, this award-winning text is an unparalleled multimedia reference for every aspect of this complex and fast-changing area.

• Offers balanced, dependable content on rapidly changing clinical science, clinical and translational research, and evidence-based medicine.
• Includes 76 new contributing authors and 14 new chapters that cover Artificial intelligence in Cardiovascular Medicine; Wearables; Influenza, Pandemics, COVID-19, and Cardiovascular Disease; Tobacco and Nicotine Products in Cardiovascular Disease; Cardiac Amyloidosis; Impact of the Environment on Cardiovascular Health, and more.
• Features a new introductory chapter Cardiovascular Disease: Past, Present, and Future by Eugene Braunwald, MD, offering his unique, visionary approach to the field of cardiology. Dr. Braunwald also curates the extensive, bimonthly online updates that include "Hot Off the Press," "Practice Updates," and "Late-Breaking Clinical Trials."
• Provides cutting-edge coverage of key topics such as proteomics and metabolomics, TAVR, diabetocardiology, and cardio-oncology.
• Contains 1,850 high-quality illustrations, radiographic images, algorithms, and charts, and provides access to 215 videos called out with icons in the print version.
• Highlights the latest AHA and ACC guidelines to clearly summarize diagnostic criteria and clinical implications.
• Provides tightly edited, focused content for quick, dependable reference. Flexible format options include either one or two volumes in print, as well as a searchable eBook with ongoing updates.
• Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

CONTENTS:

Part 1. Foundations of Cardiovascular Medicine

1. Cardiovascular Disease: Past, Present, and Future

2. Global Burden and Epidemiology of Cardiovascular Disease

3. Impact of the Environment on Cardiovascular Health

4. Clinical Trials in Cardiovascular Medicine

5. Clinical Decision Making in Cardiology

6. Impact of Healthcare Policy on Quality and Outcomes of Cardiovascular Disease

Part 2. Individualizing Approaches to Cardiovascular Disease

7. Applications of Genetics to Cardiovascular Medicine

8. Proteomics and Metabolomics in Cardiovascular Medicine

9. Principles of Drug Therapeutics, Pharmacogenomics, and Biologics

10. Biomarkers and Use in Precision Medicine

11. Artificial Intelligence in Cardiovascular Medicine

12. Wearable Devices in Cardiovascular Medicine

Part 3. Evaluation of the Patient

13. History and Physical Examination: An Evidence-Based Approach

14. Electrocardiography

15. Exercise Physiology and Testing

16. Echocardiography

17. The Chest Radiograph in Cardiovascular Disease

18. Nuclear Cardiology

19. Cardiovascular Magnetic Resonance Imaging

20. Cardiac Computed Tomography

21. Coronary Angiography and Intravascular Imaging

22. Invasive Cardiac Hemodynamics

23. Anesthesia and Noncardiac Surgery in Patients with Heart Disease

Part 4. Preventive Cardiology

24. The Vascular Biology of Atherosclerosis

25. Primary Prevention of Cardiovascular Disease

26. Systemic Hypertension: Mechanisms, Diagnosis, and Treatment

27. Lipoprotein Disorders and Cardiovascular Disease

28. Tobacco and Nicotine Products in Cardiovascular Disease

29. Nutrition and Cardiovascular and Metabolic Diseases

30. Obesity: Medical and Surgical Management

31. Diabetes and the Cardiovascular System

32. Exercise and Sports Cardiology

33. Comprehensive Cardiac Rehabilitation

34. Integrative Approaches to the Management of Patients with Heart Disease

Part 5. Atherosclerotic Cardiovascular Disease

35. Approach to the Patient with Chest Pain

36. Coronary Blood Flow and Myocardial Ischemia

37. ST-Elevation Myocardial Infarction: Pathophysiology and Clinical Evolution

38. ST-Elevation Myocardial Infarction: Management

39. Non-ST Elevation Acute Coronary Syndromes

40. Stable Ischemic Heart Disease

41. Percutaneous Coronary Intervention

42. Diseases of the Aorta

43. Peripheral Artery Diseases

44. Treatment of Noncoronary Obstructive Vascular Disease

45. Prevention and Management of Ischemic Stroke

Part 6. Heart Failure 46. Mechanisms of Cardiac Contraction and Relaxation

47. Pathophysiology of Heart Failure

48. Approach to the Patient With Heart Failure

49. Diagnosis and Management of Acute Heart Failure

50. Management of Heart Failure Patients With Reduced Ejection Fraction

51. Heart Failure with a Preserved Ejection Fraction

52. The Dilated, Restrictive, and Infiltrative Cardiomyopathies

53. Cardiac Amyloidosis

54. Hypertrophic Cardiomyopathy

55. Myocarditis

56. Cardio-Oncology: Managing Cardiotoxic Effects of Cancer Therapies

57. Cardio-Oncology: Approach to the Patient

58. Devices for Monitoring and Managing Heart Failure

59. Mechanical Circulatory Support

60. Cardiac Transplantation

Part 7. Arrhythmias, Sudden Death, and Syncope

61. Approach to the Patient with Cardiac Arrhythmias

62. Mechanisms of Cardiac Arrhythmias

63. Inheritable Cardiac Arrhythmias

64. Pharmacologic and Non-Pharmacologic Therapy of Cardiac Arrythmias

65. Supraventricular Arrhythmias 66. Atrial Fibrillation: Clinical Features, Mechanisms, and Management

67. Ventricular Arrhythmias

68. Bradyarrhythmias and Atrioventricular Block

69. Pacemakers and Implantable Cardioverter-Defibrillators

70. Cardiac Arrest and Sudden Cardiac Death

71. Hypotension and Syncope Part 8. Diseases of the Heart Valves

72. Aortic Stenosis

73. Aortic Regurgitation

74. Transcatheter Aortic Valve Replacement

75. Mitral Stenosis

76. Mitral Regurgitation

77. Tricuspid, Pulmonic, and Multivalve Disease

78. Transcatheter Therapies for Mitral and Tricuspid Valve Disease

79. Prosthetic Heart Valves

80. Cardiovascular Infections

81. Rheumatic Fever

Part 9. Diseases of the Myocardium, Pericardium, and Pulmonary Vasculature Bed

82. Congenital Heart Disease in Adolescents and Adults

83. Catheter-Based Treatment of Congenital Heart Disease

84. Cardiomyopathies Induced by Drugs or Toxins

85. Cardiovascular Abnormalities in HIV-Infected Individuals 86. Pericardial Diseases

87. Pulmonary Embolism

88. Pulmonary Hypertension

89. Sleep-Disordered Breathing and Cardiac Disease

Part 10. Cardiovascular Disease in Select Populations

90. Cardiovascular Disease in the Older Patient

91. Cardiovascular Disease in Women

92. Pregnancy and Heart Disease

93. Heart Disease in Racially and Ethnically Diverse Populations

Part 11. Cardiovascular Disease and Disorders of Other Organs

94. Influenza, Pandemics, COVID-19, and Cardiovascular Disease

95. Hemostasis, Thrombosis, Fibrinolysis, and Cardiovascular Disease

96. Endocrine Disorders and Cardiovascular Disease

97. Rheumatic Diseases and the Cardiovascular System

98. Tumors Affecting the Cardiovascular System

99. Psychiatric and Behavioral Aspects of Cardiovascular Disease

100. Neuromuscular Disorders and Cardiovascular Disease

101. Interface Between Renal Disease and Cardiovascular Illness

102. Cardiovascular Manifestations of Autonomic Disorders